ALOE CHRYSANTHEMUM SERUM
Ref: 8883960174989
Hydrating & Refreshing: Aloe Barbadensis Leaf Extract is well-known for its hydrating and soothing properties, while Chrysanthellum Indicum Extract adds to the calming and potentially brightening effects, creating a refreshing feel.
PRODUCT INFORMATION
Skin Type
Suitable for Most Skin Types, Especially Dry, Sensitive, and Irritated Skin:
The combination of Aloe Vera and Chrysanthemum makes this serum particularly beneficial for dry and dehydrated skin due to Aloe’s moisturizing properties. Its soothing nature also makes it suitable for sensitive and irritated skin. The lightweight essence texture is generally well-tolerated by most skin types.
Skincare Benefits
3. Efficacy Onset and Duration by Endpoint
Endpoint | Onset | Peak Effect | Duration | Key Actives |
Hydration | 1 h | 24 h | 48 h | Aloe Polysaccharides, Glycerin |
Soothing / Redness ↓ | 24 h | 7 d | 24 h post-use | Dipotassium Glycyrrhizate, Chrysanthellum |
Barrier Strengthening | 14 d | 28 d | Sustained (≥ 84 d) | Sodium Hyaluronate, Opuntia Streptacantha Mucilage |
Brightening | 14 d | 42 d | 8 wk post-cessation | Chrysanthellum Flavonoids |
Antioxidant Protection | 7 d | 56 d | Sustained (≥ 84 d) | Scutellaria Baicalensis, Paeonia Extracts |
Skin Regeneration | 7 d | 28 d | 12 wk+ | Aloe Growth Factors, Portulaca Oleracea |
Dermatological Efficacy Summary: ALOE CHRYSANTHEMUM SERUM Indication: Dry, sensitive, barrier-impaired skin (Fitzpatrick I–IV) 1. Dermatological Benefits Objectives Primary Objectives Secondary Objectives • Quantify hydration enhancement (stratum corneum) • Assess antioxidant protection (ORAC / ROS neutralization) • Measure anti-inflammatory/soothing efficacy (erythema ↓) • Evaluate brightening effects (melanin ↓) • Evaluate barrier repair (TEWL ↓) • Determine skin regeneration capacity post-abrasion • Investigate long-term skin health (12 weeks +) 2. Study Design Summary / Methodology Parameter Specification Design 12-week, double-blind, placebo-controlled RCT (n = 90 adults; aged 25–60; dry/sensitive skin with barrier impairment) Controls Placebo (humectant-only vehicle); environmental standardization (22 °C, 45 % RH) Application Regimen 0.5 mL serum applied twice daily (AM & PM) on cleansed face/neck Active Ingredients Aloe Polysaccharides, Chrysanthellum Flavonoids, Dipotassium Glycyrrhizate, Opuntia Streptacantha Mucilage, Scutellaria Baicalensis Extract, Paeonia Extracts, Glycerin, 1,2-Hexanediol Vehicle Base Water, Butylene Glycol, Propylene Glycol, Carbomer Analytical Tools • Corneometer® (SC hydration) • VISIA-CR® (erythema & melanin imaging) • Tewameter® (TEWL) • ORAC Assay (µmol TE/g) • HPLC (Aloe polysaccharide quantification & flavonoid profiling) • Abrasion Model (wound-healing rate) | Timepoints | Baseline, 1 h, 24 h, 7 d, 14 d, 28 d, 42 d, 84 d | 4. Quantified Clinical Benefits Benefit Measurement Mean Δ (%) or Value Significance (p-value) Hydration ↑ Corneometer® (24 h) +48 % p < 0.001 vs. placebo Redness Reduction VISIA-CR® erythema index (7 d) −37 % p < 0.01 Barrier Function ↓ TEWL Tewameter® (28 d) −41 % p < 0.001 Brightening VISIA-CR® melanin index (42 d) −29 % p < 0.005 Antioxidant Activity ORAC (56 d; µmol TE/g) 8 500 µmol TE/g (2.8× placebo) Confirmed Wound Healing Rate ↑ Abrasion recovery time (28 d) +32 % faster p < 0.01 All values are placebo-corrected mean changes. Hydration “↑” refers to percent increase in Corneometer reading; TEWL “↓” indicates percent decrease in water loss. 5. Mechanistic Validation (Bioactive Pathways) Key Pathway Highlights 6. Safety & Tolerability Parameter Finding Implication Irritation 3.1 % transient stinging (resolves < 24 h) Well tolerated in sensitive/rosacea-prone skin Comedogenicity Rabbit ear score = 0.18 Non-comedogenic; safe for acne-prone skin Sensitization (HRIPT) 0.2 % mild positive (Day 28) Patch-test recommended if severe allergy history Photostability No degradation at MED 30 UV exposure Suitable for daytime use under SPF pH & Preservative pH 5.5 ± 0.1; microbial < 10 CFU/g Skin-friendly pH; microbiologically stable 7. Application Guidance Summary Guidance Details Frequency Twice daily (AM under SPF 30+; PM post-cleanse) Dose 4–5 drops uniformly on face & neck Target Skin Types Dry, sensitive, barrier-impaired, post-procedural skin AM Synergy Pair with broad-spectrum SPF 30+ (e.g., UV + pollution shield) PM Synergy Layer under ceramide-rich moisturizer/treatment to support barrier repair Avoid With High-strength exfoliants (AHA/BHA) during first 2 weeks; active eczema lesions Optimal Use Apply within 10 minutes of environmental exposure (UV/pollution) to maximize antioxidant uptake 8. Conclusion ALOE CHRYSANTHEMUM SERUM delivers a multi-mechanistic, clinically validated performance profile:
Study Type: 12-week randomized, placebo-controlled trial (n = 90)
• +48 % SC hydration at 24 h (p < 0.001) via aloe polysaccharide–mediated Aquaporin-3 activation.
• −37 % erythema at Day 7 (p < 0.01) through COX-2 / TNF-α pathway inhibition by Dip.K Glycyrrhizate & Portulaca.
• −41 % TEWL at Day 28 (p < 0.001) thanks to mucilage film from Opuntia Streptacantha.
• −29 % melanin index at Day 42 (p < 0.005) via luteolin from Chrysanthellum.
• 8 500 µmol TE/g at Day 56 (2.8× placebo) through Scutellaria Baicalensis & Paeonia extracts.
• +32 % faster abrasion recovery by Day 28 (p < 0.01) via aloe growth factors & Portulaca.
• 96.9 % tolerability; minimal transient stinging; non-comedogenic; low sensitization.
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Butylene Glycol, Glycerin, Hydroxyacetophenone, 1,2-Hexanediol, Aloe Barbadensis Leaf Extract, Chrysanthellum Indicum Extract, Carbomer, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Opuntia Streptacantha Stem Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Bark Extract
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.