CENTELLA ASIATICA SERUM
Ref: 8883960161941
Calming & Repairing: Centella Asiatica Leaf Extract is the star ingredient, renowned for its soothing, wound-healing, and skin-repairing properties. The formula is designed to calm irritation and support skin health.
PRODUCT INFORMATION
Skin Type
Suitable for All Skin Types, Especially Sensitive, Acne-Prone, and Damaged Skin:
Centella Asiatica is well-known for its benefits for sensitive and irritated skin. It helps to reduce redness and inflammation, making it ideal for those with rosacea or eczema-prone skin. Its wound-healing properties also make it beneficial for acne-prone skin to help with post-blemish marks and overall skin recovery. The hydrating base makes it suitable for all skin types.
Skincare Benefits
3. Efficacy Onset and Duration by Endpoint
|
Endpoint |
Onset |
Peak Effect |
Duration |
Key Actives |
|
Hydration |
Immediate |
24h |
48h |
Glycerin, Sodium Hyaluronate |
|
Soothing/Redness Reduction |
24h |
7d |
24h post-application |
Centella Triterpenes |
|
Barrier Strengthening |
14d |
28d |
Sustained |
Panthenol, Acetyl Cysteine |
|
Wound Healing |
7d |
28d |
12w+ |
Asiaticoside, Madecassoside |
|
Hyperpigmentation Reduction |
14d |
42d |
8w post-cessation |
Niacinamide |
|
Antioxidant Protection |
28d |
84d |
Sustained |
Centella Polyphenols |
Dermatological Efficacy Summary: CENTELLA ASIATICA SERUM Topical Serum for Sensitive, Acne-Prone, and Post-Procedural Skin 1. Dermatological Benefits Objectives Primary Objectives Secondary Objectives 2. Study Design Summary / Methodology Parameter Specification Design Randomized, double-blind, placebo-controlled (12 weeks) Sample Size 90 adults (Fitzpatrick I–IV; acne-prone/sensitive skin) Controls Placebo = humectant-only base; ambient control (24°C, 45% RH) Dose 0.5 mL BID (morning/evening) Assessments VISIA-CR® (erythema/scarring), Corneometer®, TEWL meter, Mexameter®, ORAC assay Timepoints Baseline, 24h, 7d, 14d, 28d, 42d, 84d Analytical Validations HPLC (triterpenes), immunoassays (collagen I/III), ORAC (µmol TE/g) 4. Quantified Clinical Benefits Clinical Benefit Measurement Method Δ (%) vs. Baseline Significance Redness/Erythema Reduction VISIA-CR® erythema index (Day 7) ↓ 37% p < 0.001 vs. placebo Scar Healing VISIA-CR® scar area reduction (Day 28) ↓ 41% p < 0.005 Skin Hydration Corneometer® readings (24h) ↑ 49% p < 0.001 Barrier Repair TEWL reduction (Day 28) ↓ 38% p < 0.01 Hyperpigmentation Reduction Mexameter® melanin index (Day 42) ↓ 31% p < 0.001 Antioxidant Capacity ORAC (Day 84, µmol TE/g) 9,200 (2.7× placebo) Confirmed 5. Mechanistic Validation (Bioactive Pathways) Supporting Literature & Mechanism Notes: 6. Safety & Tolerability Parameter Outcome Implication Irritation 3.3% transient erythema (self-resolving) Safe for rosacea-prone skin Comedogenicity Non-comedogenic (Rabbit ear score = 0.2) Acne-safe Sensitization HRIPT: 0.1% sensitization rate Patch-test recommended for known allergies Photostability No active degradation at MED 50 UV Day and night use approved 7. Application Guidance Summary Parameter Recommendation Frequency 2× daily (AM pre-SPF; PM post-cleanse) Dosage 3–4 drops for face/neck Target Skin Sensitive, acne-prone, post-procedure skin Critical Use Ideal post-laser, microneedling, barrier damage Contraindications Avoid with AHAs/BHAs or open eczema lesions Synergistic Pairing SPF 50+ for pigment control; barrier creams for extreme dryness 8. Conclusion CENTELLA ASIATICA SERUM delivers rapid and sustained dermatological benefits in compromised or reactive skin types: 9. Radar
Chart: Multi-Parameter Efficacy at 8 Weeks Soothing ██████████ (95%) Barrier
Repair █████████
(88%) Hydration ██████████ (93%) Wound
Healing ████████
(81%) Brightening ███████
(75%) Antioxidant ████████
(83%) Figure:
Normalized VISIA®, Corneometer®, TEWL, and Mexameter® data (n=90)
Population: Fitzpatrick I–IV, sensitive/acne-prone skin (n=90)
Study Duration: 12 weeks (RCT)
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Glycerin, Butylene Glycol, Centella Asiatica Leaf Extract, 1,2-Hexanediol, Hydroxyacetophenone, Niacinamide, Panthenol, Sodium Hyaluronate, Acetyl Tyrosine, Acetyl Cysteine, Alanine
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.