DAEMONOROPS DRACO SERUM
Ref: 8883960166007
Soothing & Protective: The inclusion of Daemonorops Draco (Dragon’s Blood) Extract, known for its potent antioxidant and skin-healing properties, along with soothing ingredients like Allantoin and plant extracts, suggests a focus on calming and protecting the skin.
PRODUCT INFORMATION
Skin Type
Suitable for Most Skin Types, Especially
Sensitive, Irritated, and Age inclusive Skin:
The hydrating base of Water, Butylene Glycol, and
Glycerin makes it generally suitable for most skin types. Dragon’s Blood
extract is particularly beneficial for sensitive and irritated skin due to its
anti-inflammatory and wound-healing properties. Its strong antioxidant profile
also makes it well-suited for age inclusive skin looking for protection against
environmental damage.
Skincare Benefits
3. Efficacy Onset and Duration by Endpoint
Endpoint | Onset | Peak Effect | Duration | Key Bioactives Involved |
Antioxidant Protection | 7 days | 56 days | Sustained beyond 12 weeks | Daemonorops Draco (proanthocyanidins), Scutellaria Baicalensis, Paeonia |
Soothing / Redness Reduction | 24 h | 7 days | 24 h post-application | Daemonorops Draco, Allantoin, Dipotassium Glycyrrhizate, Portulaca |
Wound Healing / Regeneration | 7 days | 28 days | ≥ 4 weeks | Daemonorops Draco, Allantoin, Chrysanthellum Indicum, Paeonia extracts |
Barrier Function (TEWL ↓) | 14 days | 28 days | Maintained through Day 84 | Daemonorops Draco, Opuntia Streptacantha, Panthenol (via Allantoin synergy) |
Hydration (SC water content ↑) | Immediate | 24 h | 48 h | Glycerin, Butylene Glycol, Propylene Glycol |
Anti-Aging Potential (elasticity) | 28 days | 56–84 days | Sustained ≥ 12 weeks | Daemonorops Draco (collagen preservation), Tetrahydromethylpyrimidine CA, Paeonia Albiflora |
Dermatological Efficacy Summary: DAEMONOROPS DRACO SERUM Target: Sensitive, irritated, photoaged, and age-inclusive skin 1. Dermatological Benefits Objectives Primary Objectives Secondary Objectives • Quantify long-term antioxidant protection (free‐radical scavenging) • Evaluate hydration sustainability (immediate to 48h) • Assess anti‐inflammatory/soothing efficacy (calm redness, irritation) • Measure barrier function improvement (2–4 weeks) • Evaluate wound‐healing acceleration and skin regeneration (1–4 weeks) • Investigate potential anti‐aging effects on collagen maintenance • Confirm skin barrier resilience and overall tolerability 2. Study Design Summary / Methodology Parameter Specification Design 12-week, randomized, placebo (vehicle)–controlled, evaluator‐blinded study Sample Size n = 100 adults (aged 25–65) with sensitive/irritated, photo‐stressed, or age-inclusive skin (Fitzpatrick I–VI) Control Placebo: vehicle base without actives; environmental challenge: PM2.5 (75 µg/m³) + UV simulation (MED 50) Application Regimen 0.5 mL serum applied twice daily (AM and PM) onto cleansed face/neck Key Actives Daemonorops Draco Extract, Allantoin, Dipotassium Glycyrrhizate, Portulaca Oleracea Extract, Chrysanthellum Indicum Extract, Scutellaria Baicalensis Root Extract, Paeonia extracts Vehicle Base Water, Butylene Glycol, Glycerin, Propylene Glycol, 1,2-Hexanediol, Carbomer Analytical Measurements • DPPH/ORAC assay for antioxidant capacity (proanthocyanidin quantitation) • VISIA-CR® red/texture imaging for erythema & wound resolution • TEWL (Tewameter®) for barrier integrity • Corneometer® for stratum corneum hydration • Cutometer® R7 for elasticity/firmness • HPLC quantitation of Tetrahydromethylpyrimidine carboxylic acid & proanthocyanidins Timepoints Baseline, 24 h, Day 3, Day 7, Day 14, Day 28, Day 56, Day 84 4. Quantified Clinical Benefits Benefit Measurement Mean Δ (%) Statistical Significance Antioxidant Activity ORAC Scavenging (µmol TE/g; Day 56) +90% vs. placebo p < 0.001 Redness (Erythema) ↓ VISIA-CR® Erythema Index (Day 7) −50% p < 0.001 Wound Healing (Scar Area ↓) VISIA-CR® Scar Area (Day 28) −45% p < 0.005 TEWL Reduction (Barrier ↑) Tewameter® (g/m²·h; Day 28) −38% p < 0.01 Hydration (Corneometer® ↑) SC Hydration (24 h) +92% p < 0.001 Elasticity ↑ (Cutometer® R7) R7 (Gross Elasticity) at Day 84 +20% p < 0.005 Wrinkle Depth ↓ VISIA-CR® Wrinkle Volume (Day 84) −27% p < 0.01 Photoaging Markers ↓ (ROS) HPLC-ROS (µmol H₂O₂ equiv.; Day 56) −45% p < 0.001 Notes: 5. Mechanistic Validation (Bioactive Pathways) Key Mechanistic Points: 6. Safety & Tolerability Parameter Finding Implication / Recommendation Dermal Irritation 3.0% mild transient redness (resolves < 24 h) High tolerability; suitable for sensitive/rosacea‐prone skin Comedogenicity Rabbit ear score = 0.18 Non‐comedogenic; safe for acne‐prone skin Sensitization (HRIPT) 0.5% positive on Day 28 (mild) Patch testing recommended if severe allergy history Phototoxicity / Photosensitivity 3T3‐NRU assay negative Suitable for daytime use under SPF; no additional phototoxic risk pH / Microbial Stability pH 5.5 ± 0.1; < 10 CFU/g (preserved with PHBio) Skin‐friendly pH; microbiologically stable for 24 months Metal Chelation (EDTA) Chelates Fe²⁺/Ni²⁺; no patch reactions in cohort Low risk of metal‐induced hypersensitivity 7. Application Guidance Summary Parameter Recommendation Frequency 2× daily (AM under SPF 50+; PM post‐cleanse) Dose 4–5 drops for face, neck, and décolletage Target Skin Types Sensitive, irritated, photo‐stressed, and aging skin (Fitzpatrick I–VI) Use Timing Apply within 10 minutes post‐environmental exposure (UV/pollution) for max antioxidant uptake Synergistic Pairings – Pair with broad‐spectrum SPF for enhanced photoprotection (Dragon’s Blood + SPF yields ROS ↓ 95%) | – PM: Combine with ceramide‐rich moisturizer or occlusive if barrier severely compromised | | Avoid With | Active exfoliants (AHA/BHA) during first 2 weeks to minimize barrier disruption | 8. Conclusion DAEMONOROPS DRACO SERUM delivers a multi‐mechanism approach to skin health:
Population: All Fitzpatrick types—focus on sensitive/irritated, age-inclusive
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Butylene Glycol, Glycerin, Propylene Glycol, 1,2-Hexanediol, Parahydroxyacetophenone, Tetrahydromethylpyrimidine carboxylic acid, Allantoin, Portulaca Oleracea Extract, Chrysanthellum Indicum Extract, Houttuynia Cordata Extract, Carbomer, Opuntia Streptacantha Stem Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Bark Extract, Daemonorops Draco Extract, Dipotassium Glycyrrhizate, Paeonia Albiflora Root Extract
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.