GANODERMA SERUM
Ref: 8883960108281
Antioxidant-Rich & Revitalizing: Ganoderma Atrum (Black Ganoderma Lucidum) Extract is a potent antioxidant known for its potential to protect the skin from environmental damage and promote a healthy, revitalized complexion. The other plant extracts also contribute to antioxidant and soothing effects.
PRODUCT INFORMATION
Skin Type
Suitable for Most Skin Types, Especially Age inclusive and Stressed Skin:
The serum’s base of water, glycerin, and butylene glycol is generally well-tolerated. Black Ganoderma is particularly beneficial for age inclusive skin due to its antioxidant properties that can combat signs of aging.
It can also benefit stressed skin exposed to environmental pollutants. The inclusion of soothing extracts makes it potentially suitable for sensitive skin as well, though a patch test is always recommended.
Skincare Benefits
3. Efficacy Onset and Duration by Endpoint
Endpoint | Onset | Peak Effect | Duration | Key Actives |
Hydration | 1 h | 24 h | 48 h | Glycerin, Butylene Glycol |
Soothing / Redness Reduction | 24 h | 7 d | 24 h post-application | Portulaca oleracea, Houttuynia cordata |
Barrier Function | 14 d | 28 d | Sustained beyond 16 w | Panthenol |
Antioxidant Protection | 7 d | 56 d | Sustained beyond 16 w | Ganoderma atrum extract |
Anti-Aging (Collagen Defense) | 28 d | 112 d (≈16 w) | ≥ 16 w (end of study) | Ganoderma, Scutellaria baicalensis |
Revitalization | 56 d | 112 d (≈16 w) | 12 w post-cessation | Ganoderma, Paeonia lactiflora |
1. Dermatological Benefit Objectives Primary Objectives Secondary Objectives 2. Study Design Summary / Methodology Parameter Specification Design 16-week, randomized, double-blind, placebo-controlled trial (n = 100 adults; 35–70 years; urban pollution exposure) Controls Placebo: humectant base only; Pollution simulation: PM2.5 at 75 µg/m³ (environmental chamber) Application 0.5 mL serum applied twice daily (AM + PM) Assessments • ORAC (Oxygen Radical Absorbance Capacity) for antioxidant capacity • Corneometer® (Corneometer CM 825) for stratum corneum hydration • TEWL (Tewameter® TM 300) for barrier function • Cutometer® MPA 580 for skin elasticity (R7) • HPLC quantification of pro-MMP-1 and collagen degradation markers Timepoints Baseline (D0), 1 h, 24 h, 7 d, 2 w, 4 w, 8 w, 12 w, 16 w 4. Quantified Clinical Benefits Benefit Metric Mean Δ (% or Units) Statistical Significance Antioxidant Activity ORAC value (µmol TE/g) at Day 56 12 500 µmol TE/g 3.8× placebo (p < 0.001) Barrier Function ↓ TEWL (%) at Day 28 41 %↓ p < 0.001 Hydration ↑ Corneometer® units at 24 h +46 % p < 0.001 Redness Reduction ↓ VISIA-CR® erythema index at Day 7 39 %↓ p < 0.005 Collagen Preservation ↓ Pro-MMP-1 (HPLC) at Day 112 52 %↓ p < 0.001 Elasticity (Firmness) ↑ Cutometer® R7 at Day 112 +19 % p < 0.01 5. Mechanistic Validation (Bioactive Pathways) Validated Pathways (Literature References) 6. Safety & Tolerability Parameter Finding Recommendation Irritation 1.8 % mild tingling (resolves within 5 min) Acceptable for sensitive skin Comedogenicity Non-comedogenic (Rabbit ear score 0.18) Safe for acne-prone skin Allergenicity HRIPT-compliant (0 % sensitization, n = 50) Patch-test recommended for mushroom allergy Pollution Shield 89 % heavy-metal chelation (Pb/Cd) Especially beneficial in urban environments 7. Application Guidance Summary 8. Conclusion GANODERMA SERUM exhibits robust, clinically validated performance across multiple dermatological endpoints: Overall, GANODERMA SERUM meets primary and secondary objectives with statistically significant improvements across antioxidant capacity, barrier function, hydration, and anti-aging metrics, while maintaining an excellent safety profile. Efficacy Timeline Overview Timepoint Hydration Redness↓ Barrier↑ Antioxidant↑ Collagen Preservation Revitalization 1 h ✔ 24 h ✔✔ ✔ 7 d ✔✔ ✔ 14 d ✔ ✔ 28 d (4 w) ✔✔ ✔ 56 d (8 w) ✔✔ ✔✔ 112 d (16 w) ✔✔✔ ✔✔ ✔ ✔ 12 w Post-Cessation ✔ ✔ = Onset observed ✔✔ = Peak or strong effect ✔✔✔ = Sustained or maximal effect
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Glycerin, Butylene Glycol, Panthenol, Hydroxyacetophenone, 1,2-Hexanediol, Ganoderma Atrum Extract, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Chrysanthellum Indicum Extract, Opuntia Streptacantha Stem Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Bark Extract
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.