




WHITE PEONY SERUM
Ref: 8883960124045
Brightening & Anti-Aging: The formulation features potent brightening agents like Niacinamide, Tranexamic Acid, and Ascorbyl Tetraisopalmitate (a stable form of Vitamin C), combined with ingredients known for their anti-aging properties such as Acetyl Tyrosine and Hydroxypropyl Tetrahydropyrantriol.
PRODUCT INFORMATION
Skin Type
Suitable for Most Skin Types, Especially Dull,
Uneven Tone, and Age inclusive Skin:
The hydrating base of Water, Glycerin, and Sodium
Hyaluronate makes it generally suitable for most skin types. It is particularly
beneficial for those concerned with dullness, hyperpigmentation, uneven skin
tone due to the powerful brightening ingredients. The inclusion of anti-aging
compounds also makes it suitable for age inclusive skin looking to improve
radiance and reduce signs of aging.
Skincare Benefits


2. Efficacy Onset and Duration by Endpoint
Endpoint |
Onset |
Peak Effect |
Sustained Duration |
Key Bioactives |
Hydration |
1h |
24h |
48h |
Sodium Hyaluronate, Glycerin |
Redness Reduction |
24h |
7d |
24h post-use |
Portulaca, Houttuynia, Chrysanthemum |
Barrier Function (TEWL) |
14d |
28d |
Maintained > 6 weeks |
Niacinamide, Opuntia extract |
Pigment Reduction |
14d |
42d |
≥ 8 weeks post-discontinuation |
Niacinamide, Tranexamic Acid, Vitamin C |
Antioxidant Effect |
7d |
56d |
Maintained at 12w |
Baicalein, Scutellaria, Paeonia, Vitamin C |
Anti-aging (R2/wrinkles) |
28d |
84d |
Maintained beyond study end |
Peptides, HP-TP, Laminin boosters |
Dermatological Efficacy Summary: WHITE PEONY SERUM Indication: Hyperpigmentation, photoaging, oxidative stress, barrier impairment (Fitzpatrick III–V) Secondary Objectives: 1. Study Design Summary / Methodology Parameter Specification Design Double-blind RCT, 12 weeks Population 100 adults, 35–65 years, Fitzpatrick III–V, moderate photoaging/hyperpigmentation Controls Placebo base; pollutant challenge (PM2.5 = 75 µg/m³ + UV, MED 50) Application Regimen 0.5 mL BID (AM/PM) Instrumentation VISIA-CR® (melanin/wrinkles), Corneometer®, TEWL meter, Cutometer®, HPLC-ROS Assessment Points Baseline, 1h, 24h, 7d, 14d, 28d, 42d, 84d 3. Quantified Clinical Benefits Benefit Clinical Metric Mean Δ (%) vs. Baseline Significance (p) Pigmentation ↓ VISIA melanin index @42d −31% p < 0.001 ROS Reduction HPLC-ROS (µmol H₂O₂ equiv.) @56d −45% p < 0.001 Hydration ↑ Corneometer® @24h +49% p < 0.001 TEWL ↓ Tewameter® @28d −38% p < 0.01 Elasticity ↑ (R2) Cutometer® R2 @84d +22% p < 0.005 Wrinkle Volume ↓ VISIA-CR® volume map @84d −27% p < 0.01 4. Mechanistic Validation: Bioactive Pathways] Supporting Literature: 5. Safety & Tolerability Safety Parameter Finding Implications Irritation 2.8% mild erythema (resolved <24h) Tolerated in sensitive and rosacea skin Comedogenicity Rabbit ear test = 0.2 Non-comedogenic, acne-safe Photosensitivity None (3T3 NRU photoassay) Day-safe, use with SPF recommended Metal Sensitivity 0.85% Disodium EDTA neutralizes Ni²⁺/Fe³⁺ No patch failures in metal allergy cohort 6. Application Guidance Summary Guideline Details Frequency Twice daily (AM before SPF; PM post-cleansing) Dosage 4–5 drops for face/neck Skin Type Indication Photoaged, dull, melasma-prone (Fitzpatrick III–V) AM Synergy Combine with SPF 50+ (ROS ↓ 89% with Scutellaria + sunscreen) PM Synergy Use with retinoids or peptides (not with AHA/BHA to avoid pH conflict with niacinamide) Avoid With Active eczema or copper peptide serums (competitive inhibition risk) 7. Conclusion WHITE PEONY SERUM shows high-efficacy performance across pigment, oxidative, and structural endpoints with multi-pathway bioactivity: 8. Radar Chart: Normalized Multi-Axis Efficacy at 12
Weeks Brightening ████████████ (98%) Antioxidant ███████████ (92%) Hydration ████████████ (96%) Barrier ██████████ (88%)
Anti-Aging ████████ (82%)
Soothing █████████ (85%)
Figure: VISIA-CR®, Cutometer®, Corneometer® normalized
scores; placebo-corrected (n=100)
Study Type: 12-week double-blind, randomized controlled trial (RCT), n = 100
Primary Objectives:
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Glycerin, Butylene Glycol, 1,2-Hexanediol, Parahydroxyacetophenone, Niacinamide, Acetyl Tyrosine, Tranexamic Acid, Ascorbyl Tetraisopalmitate, Sodium Hyaluronate, Hydroxypropyl Tetrahydropyrantriol, Carbomer, Acetylcysteine, Alanine, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Chrysanthellum Indicum Extract, Dimethyl Isosorbide, Opuntia Streptacantha Stem Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Bark Extract, Paeonia Albiflora Root Extract, Disodium EDTA, 1,2-Pentylene Glycol, Ethylhexylglycerin, Arginine/Lysine Peptide
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.