




HOUTTUYNIA CORDATA SERUM
Ref: 8883960176402
Soothing & Clarifying: Houttuynia Cordata Extract is the key ingredient, known for its strong anti-inflammatory, antibacterial, and soothing properties, making it beneficial for calming irritated and acne-prone skin.
PRODUCT INFORMATION
Skin Type
Formulated for Most Skin Types, Especially Oily, Acne-Prone, and Sensitive Skin:
The lightweight formula with Houttuynia Cordata extract is particularly well-suited for oily and acne-prone skin due to its clarifying and anti-inflammatory effects.
Its soothing properties also make it beneficial for sensitive or easily irritated skin. Witch Hazel water further aids in oil control.
Skincare Benefits


3. Efficacy Onset and Duration by Endpoint
Endpoint |
Onset |
Peak Effect |
Duration |
Key Actives |
Hydration ↑ |
1 h |
24 h |
48 h |
Glycerin, Butylene Glycol |
Soothing / Redness ↓ |
24 h |
7 d |
24 h post‐application |
Houttuynia cordata, Portulaca oleracea, Chrysanthellum indicum |
Pore Minimizing |
7 d |
14 d |
48 h |
Witch Hazel tannins, Magnolia officinalis |
Acne Clarification |
7 d |
28 d |
≥ 84 d |
Houttuynia cordata, Magnolia officinalis |
Barrier Strengthening |
14 d |
28 d |
Sustained (≥ 84 d) |
Opuntia streptacantha, Scutellaria baicalensis |
Antioxidant Protection |
7 d |
56 d |
Sustained (≥ 84 d) |
Houttuynia cordata, Scutellaria baicalensis, Paeonia |
Dermatological Efficacy Summary: HOUTTUYNIA CORDATA SERUM (Dermatological Evaluation Report) 1. Dermatological Benefits Objectives Primary Objectives Secondary Objectives • Quantify anti‐inflammatory efficacy & acne clarification • Evaluate barrier enhancement • Assess pore‐minimizing effects & sebum regulation • Measure antioxidant protection & microbiome balance 2. Study Design Summary / Methodology Parameter Specification Design 12‐week, double‐blind, placebo‐controlled RCT (n = 90; 18–40 y; moderate acne with sensitivity) Controls Placebo (humectant‐only base); environmental challenge: PM2.5 at 60 µg/m³ Application 0.5 mL serum applied twice daily (AM & PM) Key Actives • Houttuynia cordata (Decanoyl acetaldehyde, Quercetin), • Portulaca oleracea, Chrysanthellum indicum • Witch Hazel tannins, Magnolia officinalis (Honokiol) • Opuntia streptacantha mucilage, Scutellaria baicalensis (Baicalein) • Paeonia extract | Vehicle Base | Water, Butylene Glycol, Glycerin, Propylene Glycol, Carbomer, 1,2‐Hexanediol | | Assessment Tools | • VISIA‐CR® (pore size, erythema) • Sebumeter® (sebum level) • Corneometer® (hydration) • Tewameter® (TEWL) • 16S rRNA sequencing (microbiome diversity) • MIC assay (C. acnes inhibition) | 4. Quantified Clinical Benefits Benefit Metric Mean Δ (%) or Value Significance (p‐value) Redness Reduction VISIA‐CR® erythema index (7 d) − 44 % p < 0.001 vs. placebo Acne Lesions ↓ Inflammatory lesion count (28 d) − 47 % p < 0.001 Pore Size Reduction VISIA‐CR® pore area (14 d) − 25 % p < 0.005 Sebum Production ↓ Sebumeter® (µg/cm²; 14 d) − 32 % p < 0.01 Barrier Function (TEWL ↓) Tewameter® (28 d) − 36 % p < 0.01 Antioxidant Activity ORAC (serum; 56 d; µmol TE/g) 9 800 µmol TE/g (3.0× placebo) p < 0.001 C. acnes Inhibition MIC reduction (in vitro; 7 d) − 78 % p < 0.001 Notes: 5. Mechanistic Validation (Bioactive Pathways) Key Pathway Highlights: 6. Safety & Tolerability Parameter Finding Recommendation Irritation 3.1 % mild transient dryness Avoid if severely dry/prone to xerosis Comedogenicity Rabbit ear score = 0.25 Non‐comedogenic; safe for acne-prone skin Microbiome Balance Cutibacterium diversity ↑ 31 % Supports reduced dysbiosis Phototoxicity Negative (3T3 NRU assay) Suitable for day/night use under SPF 7. Application Guidance Summary Guidance Recommendation Frequency 0.5 mL BID (AM under oil-free SPF; PM post-cleanse) Dose 4–5 drops on T-zone (forehead, nose, cheeks) or full face as needed Target Skin Types Oily, acne-prone, combination, or sensitive skin (Fitzpatrick I–IV) Daytime Synergy Layer under oil-free SPF (PA+++) for pollution/UV protection from PM2.5 challenge Nighttime Synergy Combine with salicylic acid (≤ 0.5 %) 2×/week for enhanced pore refinement Avoid Active rosacea, high-alcohol toners, or irritant ingredients (e.g., high‐concentration retinoids) 8. Conclusion HOUTTUYNIA CORDATA SERUM delivers a multi‐mechanistic formula backed by robust clinical evidence:
Population: n = 90 adults, 18–40 y, moderate acne with sensitivity
Duration: 12‐week randomized, placebo‐controlled trial
| Timepoints | Baseline, 1 h, 24 h, 7 d, 14 d, 28 d, 56 d, 84 d |
– “TEWL ↓” denotes percent reduction in transepidermal water loss.
– All values are placebo‐corrected mean changes ± SD.
– Sebum ↓ 32 % at 14 d (p < 0.01) through astringent tannins.
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Butylene Glycol, Glycerin, Hamamelis Virginiana (Witch Hazel) Water, Hydroxyacetophenone, 1,2-Hexanediol, Portulaca Oleracea Extract, Magnolia Officinalis Bark Extract, Houttuynia Cordata Extract, Chrysanthellum Indicum Extract, Opuntia Streptacantha Stem Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Bark Extract
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.