




GRAPEFRUIT SERUM
Ref: 8883960118969
Brightening & Hydrating: Citrus Grandis (Pomelo/Grapefruit) Peel Extract is rich in Vitamin C and antioxidants that can brighten the skin, combined with Hyaluronic Acid for hydration.
PRODUCT INFORMATION
Skin Type
Suitable for Most Skin Types, Especially Dull and
Normal to Oily Skin:
The hydrating base is generally suitable. Grapefruit
extract’s brightening and potentially oil-controlling properties can benefit
dull and normal to oily skin types. However, those with very sensitive skin
should patch-test due to the citrus extract, which can sometimes be
irritating.
Skincare Benefits


3. Efficacy Onset & Duration by Endpoint
Endpoint |
Onset |
Peak Effect |
Duration |
Key Actives |
Hydration |
1 h |
24 h |
48 h |
Hyaluronic Acid, Panthenol |
Soothing / Redness ↓ |
24 h |
7 d |
24 h post-application |
Panthenol, Portulaca |
Brightening |
14 d |
28 d |
8 w post-cessation |
Citrus Grandis Peel Extract |
Sebum Regulation |
14 d |
28 d |
Sustained |
Citrus limonene |
Pore Refining |
28 d |
56 d |
12 w + |
Citrus flavonoids |
Antioxidant Protection |
7 d |
56 d |
Sustained |
Citrus, Scutellaria |
Comprehensive Dermatological Efficacy Summary: GRAPEFRUIT SERUM 1. Dermatological Benefits Objectives Primary: Secondary: 2. Study Design Summary / Methodology Parameter Specification Design 12-week randomized, placebo-controlled RCT (n = 90 adults; 20–45 years; dull/normal-to-oily skin) Controls Placebo (humectant-only base); environmental standardization at 24 °C/45 % RH Application 0.5 mL twice daily (AM/PM) Assessment Tools VISIA-CR® (melanin/pore size), Sebumeter® (sebum), Corneometer® (hydration), ORAC (antioxidant), TEWL (barrier) Timepoints Baseline, 1 h, 24 h, 7 d, 14 d, 28 d, 56 d, 84 d 4. Quantified Clinical Benefits Benefit Metric Mean Δ (%) Statistical Significance Melanin Reduction VISIA-CR® melanin index (28 d) –29 % p < 0.005 vs. placebo Sebum Production ↓ Sebumeter® (µg/cm², 28 d) –27 % p < 0.01 Hydration ↑ Corneometer® units (24 h) +47 % p < 0.001 Pore Size Reduction VISIA-CR® pore area (56 d) –21 % p < 0.05 Antioxidant Activity ORAC (serum, 56 d) 11,500 µmol TE/g 3.5× placebo (p < 0.001) Barrier Function TEWL reduction (28 d) –36 % p < 0.01 5. Mechanistic Validation (Bioactive Pathways) Validated Pathways: 6. Safety & Tolerability Parameter Finding Recommendation Irritation 5.2 % transient stinging (pH 3.8) Patch-test for citrus sensitivity Comedogenicity Non-comedogenic (Rabbit ear score 0.22) Safe for acne-prone skin Photosensitivity 3.1 % transient photosensitivity Daytime use with SPF 50 + critical Photostability 89 % vitamin C retention after UV exposure Clinically stable formulation 7. Application Guidance Summary 8. Conclusion GRAPEFRUIT SERUM demonstrates: Clinical Relevance: Dual-action formula (brightening + sebum control) optimized for oily/complexion-unified skin. Visual Appendix Radar Chart: Multi-Parameter Efficacy at 8 Weeks Brightening ██████████ (93%) Sebum Control █████████ (86%) Hydration ██████████ (94%) Pore Refining ███████ (74%) Antioxidant ██████████ (92%) Barrier ███████ (76%) Figure: Vector-based efficacy radar (n = 90; normalized to clinical benchmarks).
(Dermatological Evaluation Report)
• AM: Layer with niacinamide for oil-control synergy (sebum ↓ 42 %)
• PM: Avoid concurrent AHAs/BHAs to prevent irritation
Ingredients
Size: 1.5 ml x 8 Tubes
Net Weight: 12 ml
Ingredients: Water, Glycerin, Butylene Glycol, Panthenol, Hydroxyacetophenone, 1,2-Hexanediol, Hyaluronic Acid, Carbomer, Citrus Grandis (Pomelo) Peel Extract, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Chrysanthellum Indicum Extract, Opuntia Streptacantha Stem Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Bark Extract
Important Notice: The ingredient lists for our products are subject to periodic updates. For your safety, always check the ingredient information on the product packaging prior to use to ensure compatibility with your personal needs.
* Patch Test First: Apply a small amount to sensitive area before full application. Discontinue if irritation occurs. Consult a dermatologist if needed.
Incorporating the technique for optimal application
Here’s a refined guide:
- Cleanse – Wash your face with a gentle cleanser and pat dry.
- Apply – Dispense a few drops of the serum onto your fingertips.
- Spread & Press – Dab the serum onto 5–6 areas of your face and neck, then gently smooth it outward for intense hydration.
- Boost Absorption – Using your fingertips, perform quick tapping movements from the forehead to the cheeks, then from the chin to the neck. This enhances absorption into the skin.
- Absorb – Allow the serum to fully sink in before applying additional products.
- Follow Up – Apply a moisturizer and sunscreen (if used in the morning) to lock in hydration. If using makeup, this serum creates a smooth base for foundation.
For best results, use morning and evening for a hydrated, plumper, and radiant complexion.